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Without the anabolic activity of true SARMs and steroids, Cardarine is not a muscle growth compoundand should not be used by a well-trained lifter, as it tends to suppress the growth hormone response from the growth-stimulating hormone.Cardarine is a steroid-like anabolic agent with a variety of biological activities that have been reported in the literature. It has been shown to increase growth hormone production, blood plasma volume, IGF-1 binding protein, T3 binding protein, insulin receptor and IGF-1 binding protein 3, serum IGFBP3, IGFBP8, IGFBP4, IGFBP5, IGFBP6, IGFBP8 mRNA transcripts in cultured muscle cells, muscle mRNA accumulation in skeletal muscle, and the increase in muscle mass and protein synthesis in vivo. It is also possible that Cardarine increases insulin sensitivity by increasing the expression of insulin receptor substrate 1 and its downstream targets in muscle cells.Cardarine also appears to be non-toxic, though its metabolism may be more complex than that of testosterone. Because the half-life of Cardarine is approximately 24 hours, it can be easily ingested at the same time of day and day-night as testosterone. Because testosterone and Cardarine are metabolized differently, it is also possible to combine the two.It is possible that the growth-promoting actions of Cardarine that have been reported in the literature are primarily due to its interaction with the testosterone system and not due to direct effects on body fat levels or the rate of fat loss. It is also possible that this growth-promoting effect of Cardarine may be due to the lack of side effects and negative effects of this compound compared to other anabolic agent.Cardarine has also been shown to inhibit androgen receptor phosphorylation in cultured cell models. This indicates that this compound could act as an androgen receptor antagonist which may be the reason why it has been shown to work so well for male athletes.Despite this potential activity, Cardarine is not well tolerated nor is it well tested in humans. Because of this, Cardarine is best used with extreme caution. Because of this and because of the effects that this compound has on human tissue cells, Cardarine should only be used on patients that are suffering from severe anabolic deficiency and that are in compliance with all recommendations for the use of anabolic agents, such as the U.S. FDA-approved labeling guidelines for anabolic agents.Important Safety Points of CardarineCardarine, like other testosterone boosters, does not appear to have any negative effects on the heart. It shouldRelated Article: